NRS series

Micro-Raman spectrometer

With over fifty years of experience in spectroscopy and using the most advanced technology, JASCO offers the best solutions for micro-Raman analysis with a complete range of micro-Raman systems.

Raman spectroscopy is capable of measuring impossible small site in the infrared microscope. Raman spectroscopy with such features is becoming popular as a general-purpose analytical instruments, but micro-Raman spectrophotometer traditional took skill optimization of measurement conditions, optical adjustment and data analysis. The NRS series will change the way Raman is used for many different applications.

All NRS Series Raman instruments include a color CCD sample viewing system with image capture capability. Utilizing the same basic optical system, JASCO designed a family of micro-Raman spectrometers that offer a range of capabilities from simple, single laser, single grating instruments to advanced research grade systems with low wave number measurement, wavelength extension from the deep UV to NIR, and the ability to use or add up to six lasers.

A range of micro Raman models are available:

NRS-4100 Dispersive Raman Spectrometer

For the first time, the new NRS-4100 brings together a number of critical elements to make Raman spectroscopy accessible not only to experienced spectroscopists, but also to first-time users.

In Raman spectrometry, sample preparation is generally considered to be much easier than for infrared spectroscopy and unlike FTIR microscopy, Raman offers greatly improved spatial resolution. As a result, the use of Raman spectrometry is rapidly spreading as the analytical technique of choice for materials analysis. One of the factors which has previously held back the adoption of laser Raman instruments is the skill set required for optical adjustment, measurement optimization and data analysis. The NRS-4100 will change the way Raman is used for many different applications.

Class 1 laser safety

The first thing you will notice is a Class 1 safety cabinet more commonly associated with high-end Raman systems, but that is only the beginning. Once you operate the interlock switch, the door opens to reveal a wealth of powerful tools

Rigid optical bench and laser image

The purposed designed microscope is completely rigid to prevent flexing, this is not the case with other systems built around an optical microscope. The NRS-4100 also offers observation of the laser spot (not generally available) to ensure it is perfectly aligned to the target sample and with X/Y spatial resolution to 1 µm (Z=1.5 µm). Switching between observation and measurement modes is completely automatic and can be done with the safety cabinet closed.

The NRS-4100 offers standard configurations that include the typical 532/785nm laser combination with matching edge or notch filters and an option for a third laser. All laser wavelengths are automatically selected in the software and, once selected, the optical system including the laser is automatically aligned for optimal throughput and resolution. Four software selectable gratings control the spectral range and resolution from 8000 to 100 cm-1 as standard (8000 to 50 cm-1 as an option). With a direct-drive rotary encoder, the wavelength reproducibility is ±0.2cm-1

New 457 nm laser for fluorescence rejection and patented fluorescence rejection algorithm.

JASCO has developed new and novel (patented) mechanisms to deal with sample fluorescence. As with other Raman systems, we can utilize laser wavelengths of 785 nm and up to 1064 nm, but we have recently incorporated a 457 nm laser option that offers higher Raman signal, improved spatial resolution and much lower fluorescence for many different sample types. Selecting optional excitation laser wavelengths is only one of the ways JASCO minimizes fluorescence interference. The Fluorescence Rejection algorithm (patented) included in the Spectra Manager II collection and analysis software effectively removes or minimizes fluorescence regardless of the laser wavelength used.

Flexible sampling options

With a choice of refractive objectives, both micro and macro measurements are possible as well as options for long working distance objectives for heated sample stages and other sampling accessories. The NRS-4100 can also be specified with a manual sample stage or the PC-controlled, automated XYZ mapping stage in addition to a modified stage (80 mm working distance) to accommodate a variety of heating and cooling sample accessories.

Powerful ‘UserAssist’ control for experienced spectroscopists and new users alike

The ‘UserAssist’ software aids the user in setting up the NRS-4100 for sample measurement; a simple sequence guide takes you through setup and optimization of measurement parameters with helpful advice and tips, such as a warning if you have the laser intensity set too high. When each of the parameters has been set, the NRS-4100 automatically selects the laser and matching notch filter, the grating for the appropriate resolution, focuses on the sample and then the spectral measurement is performed.

‘Simple Search’ function

The new ‘Simple Search’ function is used with the automated XYZ stage. A new algorithm developed by JASCO (patent pending) analyzes the microscopic image and automatically selects measurement position(s) based on the size, contrast and/or color of the target material. The user simply clicks the measurement button to execute spectral measurements of the desired sample positions.

Chemical Image identification and functional groups registry

To provide faster Raman image processing, the Imaging Analysis software includes a ‘Registry’ of possible functional groups or other relevant compound information based on peak height or area calculations. After a peak height or area calculation is developed, it can be saved to the Registry for future analysis use. The registry includes the peak calculation information and a ‘label’ describing the relevant vibrational motion. Image maps can be developed from mapping data simply by clicking on the desired, registered calculation to obtain a false color image of the peak intensity data for the registered calculation.

NRS-5000 and NRS-7000 Series Raman


Resolution: 1 cm-1 / 0.4 cm-1 (optional)
Measurement range: 50 to 8000 cm-1


Resolution: 1 cm-1 / 0.4 cm-1 (optional)
Measurement range: 10 to 8000 cm-1


Resolution: 0.7 cm-1/ 0.3 cm-1(optional)
Measurement range: 50 to 8000 cm-1


Resolution: 0.7 cm-1/ 0.3 cm-1(optional)
Measurement range: 5 to 8000 cm-1

The performance and functions expected on a micro-Raman spectrometer are all provided with the NRS-5000 and 7000 series Raman systems, assuring consistent performance for rapid acquisition of high quality data with automated system control and minimal optical adjustments.

For application expansion, an automated multi-grating turret, 2 internally mounted detectors and a maximum of 8 lasers ranging from the UV through the NIR are capable of integration with the instrument system, all optical components are PC controlled for maximum flexibility with minimum user interaction.

NRS-5000/7000 Series Features

  • Research-grade model assuring high spectral quality
  • Exceptional wavenumber accuracy with a high-precision rotary-encoder direct drive mechanism
  • Low wavenumber measurement (NRS-5200/7200)
  • Auto-alignment of microscope laser introduction optics and Raman scattering light path
  • Wavenumber calibration using an integrated Ne lamp
  • Unique Dual Spatial Filter (DSF) for higher spatial resolution than conventional confocal optics
  • Patented Spatial Resolution Image (SRI) function for simultaneous observation of sample image, laser spot and aperture image
  • Full range of options including macro-Raman measurement unit and fiber optic probes

RMP-300 series Portable Raman Spectrometer


  • Compact portable type
  • Spectrograph with fixed wavenumber spectral range
  • Resolution: 3 cm-1 (RMP-310), 4 cm-1 (RMP-315)


  • High end model for laboratory analysis
  • Resolution: 3 cm-1 (RMP-330), 4 cm-1 (RMP-335)
  • Dual-grating monochromator (factory option)


  • Middle class model with wavenumber scanning capability  
  • Resolution: 3 cm-1 (RMP-320), 4 cm-1 (RMP-325)
  • Dual-grating monochromator (factory option

The RMP-300 Series portable Raman spectrometer system incorporates a fiber optic probe with a small X-Y-Z stage, compact laser, a high-throughput spectrograph and Peltier-cooled CCD detector. No special utilities such as coolants are required allowing the system to be used almost anywhere. The flexibility of optical fiber coupling enables remote measurements by locating the probe right at the sample. The fiber optic probe features an integrated CCD video camera for sample positioning and capturing of digital sample images. All operations are performed by the dedicated software package based on JASCO Spectra Manager™ II.

The RMP-300 Series consists of six models, the RMP-310, 315, 320, 325, 330, and 335, ranging from small, portable units suitable for in-situ measurements to research-grade systems to provide capabilities for a wide range of application requirements.

The RMP-300 system is controlled using Spectra Manager™ II, JASCO’s powerful Windows based cross-platform spectroscopy software package. The system is capable of both laboratory work and on-site measurements in the fields of process control, QC, forensics, art conservation and mineralogy.

System features

  • Portable Raman spectrometer: Simple, high-speed in-situ measurements
  • Fiber optic probe for remote Raman measurements: Non-destructive sample measurements
  • High-throughput spectrograph with compact laser and CCD detector
  • No special utilities required: compact and lightweight
  • Integrated CCD camera for sample positioning, digital image capture of the sample
  • Remote measurements using fiber optic probe (optical fiber length: 1 – 100 meters)
  • Screening of materials
  • On line process monitoring
  • Non-destructive measurement of a sample that cannot be ‘sampled’ or moved
  • In-situ analysis (time-course measurements)
  • Microscope observation using integrated CCD camera